Topical antimicrobial agent vs systemic antimicrobial agent: Resolution of infection
It is very uncertain whether topical antimicrobial agent changes resolution of infection compared with systemic antimicrobial agent (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical antimicrobial agent vs systemic antimicrobial agent Resolution of infection · Foot ulcers in people with diabetes It is very uncertain whether topical antimicrobial agent changes resolution of infection compared with systemic antimicrobial agent (very low certainty). Topical antimicrobial agents for treating foot ulcers in people with diabetes (2017) · Cochrane Headline outcomes only | RR 1.51 [0.91, 2.49] | 2 studies · 102 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Topical antimicrobial agents for treating foot ulcers in people with diabetes 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.