Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Bone, Joint and Muscle Trauma

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No studies found 4 · 57.1%GRADE not reported 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Timing of wound closure (immediate vs delayed)

Deep surgical site infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes deep surgical site infection compared with delayed) (very low certainty).

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
RR 0.82 [0.37, 1.8]
2 studies · 458 participants
Very low

Timing of wound closure (immediate vs delayed)

Delayed or non‐union (medium term) · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes delayed union or non‐union compared with delayed) (very low certainty).

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
RR 1.13 [0.83, 1.55]
1 study · 387 participants
Very low

Timing of wound closure (immediate vs delayed)

Unplanned operations at 12 months · adults with open long bone fractures of the upper and lower limbs

The review found no eligible studies for this question.

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Timing of wound closure (immediate vs delayed)

Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes adverse events ‐ superficial infection compared with delayed) (very low certainty).

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
RR 6.45 [0.35, 120.43]
1 study · 71 participants
Very low

Timing of wound closure (immediate vs delayed)

Return to work · adults with open long bone fractures of the upper and lower limbs

The review found no eligible studies for this question.

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Timing of wound closure (immediate vs delayed)

Limb function at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs

The review found no eligible studies for this question.

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Timing of wound closure (immediate vs delayed)

HRQoL at 6 or 12 months · adults with open long bone fractures of the upper and lower limbs

The review found no eligible studies for this question.

1 finding from 1 review

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found