Findings

What do systematic reviews say?

3 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 1 · 16.7%Moderate 3 · 50%High 1 · 16.7%

Tacrolimus 0.03% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

4 findings from 1 review

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 2.05 [1.36, 3.08]
1 study · 411 participants
Moderate
Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 2.58 [1.96, 3.38]
2 studies · 790 participants
Moderate
Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 0.45 [0.13, 1.57]
2 studies · 409 participants
Very low

Show 1 more finding

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 1 [0.85, 1.19]
1 study · 265 participants
Low

Tacrolimus 0.03% vs corticosteroids

Adverse effects ‐ burning · people with atopic dermatitis

1 finding from 1 review

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
2.48 [1.96, 3.14]
5 studies · 1883 participants
High

Tacrolimus 0.03% vs corticosteroids

Participant's self‐assessment of global response of improvement: tacrolimus 0.03% 2x/day versus hydrocortisone acetate 1% 2x/day · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher participant's self‐assessment of global response of improvement:… compared with corticosteroids (moderate certainty).

1 finding from 1 review

Topical tacrolimus for atopic dermatitis 2015 · Cochrane Headline outcomes only
RR 1.64 [1.41, 1.9]
1 study · 416 participants
Moderate