Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 100%Moderate 0 · 0%High 0 · 0%

Withdrawals due to adverse events · adults with panic disorder

TCAs may leads to higher number of dropouts due to adverse effects compared with benzodiazepines (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 2.1 [1.13, 3.93]
2 studies · 848 participants
Low

Withdrawals due to adverse events · adults with panic disorder

TCAs showed no clear difference in number of dropouts due to adverse effects compared with SSRI (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.43 [0.82, 2.48]
5 studies · 476 participants
Low