What do systematic reviews say?

Systemic or topical corticosteroids vs placebo or control

Systemic or topical corticosteroids may leads to lower risk of secondary hemorrhage; oral corticosteroids compared with placebo or control treatment (low certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 0.63 [0.4, 0.97]
  3 studies · 323 participants
  Low

Systemic or topical corticosteroids vs placebo or control

It is very uncertain whether systemic or topical corticosteroids changes risk of secondary hemorrhage; topical corticosteroids compared with placebo or control treatment (very low certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 0.29 [0.05, 1.53]
  2 studies · 151 participants
  Very low

Systemic or topical corticosteroids vs placebo or control

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 166 participants
  Low
• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Very low

Systemic or topical corticosteroids vs placebo or control

Systemic or topical corticosteroids showed no clear difference in final visual acuity between 20/20 and 20/40 at end of treatment;… compared with placebo or control treatment (low certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 1.01 [0.84, 1.23]
  1 study · 41 participants
  Low

Systemic or topical corticosteroids vs placebo or control

Systemic or topical corticosteroids showed no clear difference in final visual acuity between 20/20 and 20/25 at end of treatment;… compared with placebo or control treatment (low certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 1.02 [0.94, 1.11]
  1 study · 111 participants
  Low

Systemic or topical corticosteroids vs placebo or control

Systemic or topical corticosteroids showed no clear difference in short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (low certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 1.2 [0.97, 1.49]
  2 studies · 277 participants
  Low

Systemic or topical corticosteroids vs placebo or control

It is very uncertain whether systemic or topical corticosteroids changes short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (very low certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 0.75 [0.38, 1.47]
  1 study · 34 participants
  Very low