Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 23 findings · 2 reviews · Headline outcomes only

No studies found 8 · 34.8%GRADE not reported 6 · 26.1%Very low 8 · 34.8%Low 1 · 4.3%Moderate 0 · 0%High 0 · 0%

Synbiotic vs placebo

Global improvement or treatment success, as defined by primary study · children with chronic constipation without a physical explanation

Synbiotics may leads to higher global improvement or treatment success, as defined by primary study compared with placebo (low certainty).

1 finding from 1 review

Synbiotic vs paraffin

Global assessment of treatment success · children with chronic constipation without a physical explanation

It is very uncertain whether synbiotics changes global improvement or treatment success, as defined by primary studies compared with paraffin (very low certainty).

1 finding from 1 review