Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 46 findings · 9 reviews · Oral and maxillofacial surgery

No studies found 37 · 80.4%GRADE not reported 6 · 13%Very low 0 · 0%Low 3 · 6.5%Moderate 0 · 0%High 0 · 0%

Open (surgical) reduction and fixation vs Closed (non-surgical) treatment

Outcome not reported · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement

The review found no eligible studies for this question.

1 finding from 1 review
  • "There were no studies comparing different types of closed interventions with one another or comparing open and closed interventions." "We found no studies that compared surgical with non-surgical treatments."
    0 studies
    No studies found

Drain use vs No drain

Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal

Surgical drain (tube or gauze) led to higher maximum mouth opening (mean) compared with no drain; GRADE not reported.

1 finding from 1 review

Drain use vs No drain

Postoperative pain (mean) · Adults with mandibular third molars requiring removal

Surgical drain (tube or gauze) showed no clear difference in postoperative pain (mean) compared with no drain; GRADE not reported.

1 finding from 1 review

Any experimental intervention (surgical or non-surgical) vs active control

Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Overall survival · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Disease-free survival · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Resectability · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Quality of life · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Adverse events · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Complete remission · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Partial reduction · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

Recurrence · Patients with a pathological diagnosis of central giant cell granuloma (CGCG) of the jaws

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Undesirable outcomes associated with removal (alveolar osteitis/postoperative infection, nerve injury, damage to adjacent teeth, bleeding, osteonecrosis, inflammation/infection) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Other pathological changes associated with retention (pericoronitis, root resorption, cyst formation, tumour formation, inflammation/infection) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review