Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Drugs and Alcohol

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No studies found 3 · 42.9%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%

Summary of findings table – disulfiram vs naltrexone

Continuous abstinence from cocaine (number of participants who had achieved and maintained abstinence for at least three weeks at the end of treatment) · patients with the treatment of cocaine dependence

The review found no eligible studies for this question.

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table – disulfiram vs naltrexone

Point abstinence (number of participants who were abstinent at the end of the treatment) · patients with the treatment of cocaine dependence

The review found no eligible studies for this question.

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table – disulfiram vs naltrexone

Acceptability ‐ total dropouts · patients with the treatment of cocaine dependence

It is very uncertain whether summary of findings table – disulfiram changes dropout for any reason (number of participants who did not complete… compared with naltrexone (very low certainty).

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
RR 0.86 [0.56, 1.32]
3 studies · 131 participants
Very low

Summary of findings table – disulfiram vs naltrexone

Dropouts due to adverse events · patients with the treatment of cocaine dependence

It is very uncertain whether summary of findings table – disulfiram changes dropout due to adverse events (number of participants who did not… compared with naltrexone (very low certainty).

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
RR 0.5 [0.07, 3.55]
1 study · 8 participants
Very low

Summary of findings table – disulfiram vs naltrexone

Adverse events as N of participants with at least one adverse event objective · patients with the treatment of cocaine dependence

The review found no eligible studies for this question.

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table – disulfiram vs naltrexone

Frequency of cocaine use (mean number of days or weeks of cocaine use at the end of treatment) · patients with the treatment of cocaine dependence

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 123 participants
Low

Summary of findings table – disulfiram vs naltrexone

Amount of cocaine use (mean weight of cocaine used or money spent on cocaine at the end of treatment) · patients with the treatment of cocaine dependence

1 finding from 1 review

Disulfiram for the treatment of cocaine dependence 2024 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 123 participants
Low