What do systematic reviews say?

PUFA vs placebo

Summary of findings table ‐ PUFA showed no clear difference in side effects – overall compared with placebo (moderate certainty).

• Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2023 · Cochrane Headline outcomes only
  RR 1.02 [0.69, 1.52]
  8 studies · 591 participants
  Moderate