Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 4 · 57.1%Low 0 · 0%Moderate 1 · 14.3%High 0 · 0%

HFNC vs continuous positive airway pressure (CPAP)

Death · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 439 participants
GRADE not reported

HFNC vs continuous positive airway pressure (CPAP)

Treatment failure · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes treatment failure compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
RR 0.98 [0.47, 2.04]
3 studies · 452 participants
Very low

HFNC vs continuous positive airway pressure (CPAP)

Chronic lung disease · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 375 participants
GRADE not reported

HFNC vs continuous positive airway pressure (CPAP)

Duration of any form of respiratory support (any form of non‐invasive respiratory support with or without supplemental oxygen) · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 530 participants
Very low

HFNC vs continuous positive airway pressure (CPAP)

ICU length of stay (general intensive care patients) · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 452 participants
Moderate

HFNC vs continuous positive airway pressure (CPAP)

Adverse events ‐ nasal trauma · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ nasal trauma compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
RR 0.16 [0.04, 0.66]
1 study · 78 participants
Very low

HFNC vs continuous positive airway pressure (CPAP)

Adverse events ‐ abdominal overdistention · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ abdominal overdistention compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes only
RR 0.22 [0.07, 0.71]
1 study · 78 participants
Very low