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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: all ECMO studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: all ECMO studies compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VV ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: VV ECMO subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VA ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: VA ECMO subgroup compared with conventional care (low certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality at 6 months (subgroup) · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: ECPR subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

Major hemorrhage · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to higher major hemorrhage: all available studies compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

Neurologic injury: all available studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in neurologic injury: all available studies compared with conventional care (moderate certainty).

1 finding from 1 review