Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 1 · 14.3%Moderate 4 · 57.1%High 1 · 14.3%

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Hospital readmission · patients with schizophrenia

It is very uncertain whether summary of findings table ‐ Antipsychotic dose reduction changes service use ‐ readmission to hospital (combined time points) compared with dose continuation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Withdrawals due to adverse events · patients with schizophrenia

Summary of findings table ‐ Antipsychotic dose reduction probably leads to higher adverse effect ‐ leaving the study early due to adverse effects ‐… compared with dose continuation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Global state ‐ number of participants with relapse/exacerbations of psychosis (combined time points) · patients with schizophrenia

Summary of findings table ‐ Antipsychotic dose reduction may leads to higher global state ‐ number of participants with relapse/exacerbations of… compared with dose continuation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points) · patients with schizophrenia

Summary of findings table ‐ Antipsychotic dose reduction probably leads to higher leaving the study early ‐ for any reason ‐ overall acceptability… compared with dose continuation (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Participants with at least some Side Effects · patients with schizophrenia

Summary of findings table ‐ Antipsychotic dose reduction showed no clear difference in adverse effects ‐ number of participants with at least 1 adverse… compared with dose continuation (moderate certainty).

1 finding from 1 review