Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

41 questions · 42 findings · 4 reviews

No studies found 6 · 14.3%GRADE not reported 0 · 0%Very low 18 · 42.9%Low 7 · 16.7%Moderate 11 · 26.2%High 0 · 0%

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Patient satisfaction: delayed (prescription collection) versus no antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to higher patient satisfaction: delayed (prescription collection) versus no… compared with no antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Antibiotic use: delayed (all strategies) versus immediate antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to lower antibiotic use: delayed (all strategies) versus immediate antibiotics compared with immediate antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Patient satisfaction: delayed (all strategies) versus immediate antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics showed no clear difference in patient satisfaction: delayed (all strategies) versus immediate… compared with immediate antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Reconsultations · respiratory infections

Summary of findings table ‐ Delayed antibiotics showed no clear difference in reconsultation rate: delayed (all strategies) versus immediate… compared with immediate antibiotics (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Antibiotic use: delayed (all strategies) versus no antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to higher antibiotic use: delayed (all strategies) versus no antibiotics compared with no antibiotics (moderate certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Adverse events considered non‐serious (penicillin versus cefotaxime) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus cefotaxime) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Adverse events considered non‐serious (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Non‐serious adverse events Maximum · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

All‐cause mortality (penicillin versus a cephalosporin (cefotaxime or ceftriaxone)) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (penicillin versus a cephalosporin (cefotaxime… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

All‐cause mortality (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (penicillin versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

All‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes all‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Serious adverse events (nosocomial infection) (penicillin versus cefotaxime) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Serious adverse events (nosocomial infection) (penicillin versus doxycycline) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (penicillin versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs other antibiotics

Serious adverse events (nosocomial infection) (doxycycline versus cefotaxime) · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (doxycycline versus… compared with other antibiotics (very low certainty).

1 finding from 1 review

Antibiotics vs no antibiotics

Clinical pregnancy rate · embryo transfer (ET) in assisted reproductive technology (ART)

Summary of findings table ‐ Antibiotics showed no clear difference in clinical pregnancy rate (CPR) compared with control (no antibiotics) (low certainty).

1 finding from 1 review

Antibiotics vs no antibiotics

Genital Tract Colonisation · embryo transfer (ET) in assisted reproductive technology (ART)

It is very uncertain whether summary of findings table ‐ Antibiotics changes genital tract colonization compared with control (no antibiotics) (very low certainty).

1 finding from 1 review