Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Kidney and Transplant

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 3 · 37.5%Low 4 · 50%Moderate 0 · 0%High 0 · 0%

Summary of findings ‐ Lanthanum vs calcium

Coronary artery calcification score · people with CKD

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Summary of findings ‐ Lanthanum vs calcium

Death (all causes) · people with CKD

Summary of findings ‐ Lanthanum showed no clear difference in death (all causes) compared with calcium (low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 0.76 [0.18, 3.11]
6 studies · 505 participants
Low

Summary of findings ‐ Lanthanum vs calcium

Cardiovascular mortality · people with CKD

The review found no eligible studies for this question.

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings ‐ Lanthanum vs calcium

Hypercalcaemia · people with CKD

Summary of findings ‐ Lanthanum may leads to lower hypercalcaemia compared with calcium (low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 0.16 [0.06, 0.43]
8 studies · 1347 participants
Low

Summary of findings ‐ Lanthanum vs calcium

Nausea · people with CKD

Summary of findings ‐ Lanthanum showed no clear difference in nausea compared with calcium (low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 1.65 [0.95, 2.89]
5 studies · 1191 participants
Low

Summary of findings ‐ Lanthanum vs calcium

Vomiting · people with CKD

It is very uncertain whether summary of findings ‐ Lanthanum changes vomiting compared with calcium (very low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 3.88 [0.48, 31.7]
2 studies · 1058 participants
Very low

Summary of findings ‐ Lanthanum vs calcium

Constipation · people with CKD

Summary of findings ‐ Lanthanum showed no clear difference in constipation compared with calcium (low certainty).

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
RR 0.79 [0.5, 1.26]
5 studies · 1213 participants
Low

Summary of findings ‐ Lanthanum vs calcium

Serum phosphate level · people with CKD

1 finding from 1 review

Phosphate binders for preventing and treating chronic kidney disease‐mineral and bone disorder (CKD‐MBD) 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 400 participants
Very low