Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 3 · 50%Moderate 3 · 50%High 0 · 0%

Warfarin vs aspirin

All‐cause mortality · patients with heart failure with sinus rhythm

Summary of findings: warfarin showed no clear difference in all‐cause mortality compared with aspirin (moderate certainty).

1 finding from 1 review

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm 2016 · Cochrane Headline outcomes only
RR 1 [0.89, 1.13]
4 studies · 3663 participants
Moderate

Warfarin vs aspirin

Non‐fatal cardiovascular events · patients with heart failure with sinus rhythm

Summary of findings: warfarin showed no clear difference in non‐fatal cardiovascular events (non‐fatal stroke, myocardial… compared with aspirin (moderate certainty).

1 finding from 1 review

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm 2016 · Cochrane Headline outcomes only
RR 0.79 [0.63, 1]
4 studies · 3663 participants
Moderate

Warfarin vs aspirin

Major bleeding · patients with heart failure with sinus rhythm

Summary of findings: warfarin probably leads to higher major bleeding events compared with aspirin (moderate certainty).

1 finding from 1 review

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm 2016 · Cochrane Headline outcomes only
RR 2 [1.44, 2.78]
4 studies · 3663 participants
Moderate

Warfarin vs clopidogrel

All‐cause mortality · patients with heart failure with sinus rhythm

Summary of findings: warfarin showed no clear difference in all‐cause mortality compared with clopidogrel (low certainty).

1 finding from 1 review

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm 2016 · Cochrane Headline outcomes only
RR 0.93 [0.72, 1.21]
1 study · 1064 participants
Low

Warfarin vs clopidogrel

Non‐fatal cardiovascular events · patients with heart failure with sinus rhythm

Summary of findings: warfarin showed no clear difference in non‐fatal cardiovascular events (non‐fatal stroke, myocardial… compared with clopidogrel (low certainty).

1 finding from 1 review

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm 2016 · Cochrane Headline outcomes only
RR 0.85 [0.5, 1.45]
1 study · 1064 participants
Low

Warfarin vs clopidogrel

Major bleeding · patients with heart failure with sinus rhythm

Summary of findings: warfarin may leads to higher major bleeding events compared with clopidogrel (low certainty).

1 finding from 1 review

Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm 2016 · Cochrane Headline outcomes only
RR 2.47 [1.24, 4.91]
1 study · 1064 participants
Low