Summary of findings: levodopa vs other dopamine agonists
Total sleep time, next night; · patients with restless legs syndrome
1 finding from 1 review
- no estimate extracted1 study · 11 participantsVery low
Findings
What do systematic reviews say?
7 questions · 7 findings · 1 reviews
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 2 · 28.6%Moderate 4 · 57.1%High 0 · 0%
Summary of findings: levodopa vs other dopamine agonists
Adverse effects (drop‐outs due to adverse effects4) · patients with restless legs syndrome
Summary of findings: levodopa probably leads to lower number of drop outs due to adverse events compared with other dopamine agonists (moderate certainty).
1 finding from 1 review
- OR 0.593 studies · 504 participantsModerate
Summary of findings: levodopa vs other dopamine agonists
Clinical Global Impressions ‐ Improvement of condition (CGI‐I) Rating of 1 = very much improved to 7 = very much worse · patients with restless legs syndrome
1 finding from 1 review
- no estimate extracted1 study · 344 participantsModerate
Summary of findings: levodopa vs other dopamine agonists
Quality of sleep · patients with restless legs syndrome
1 finding from 1 review
- no estimate extracted1 study · 344 participantsLow
Summary of findings: levodopa vs other dopamine agonists
QoL · patients with restless legs syndrome
1 finding from 1 review
- no estimate extracted1 study · 314 participantsModerate
Summary of findings: levodopa vs other dopamine agonists
IRLS · patients with restless legs syndrome
1 finding from 1 review
- no estimate extracted2 studies · 383 participantsModerate
Summary of findings: levodopa vs other dopamine agonists
Periodic limb movements per hour of time in bed · patients with restless legs syndrome
1 finding from 1 review
- no estimate extracted1 study · 39 participantsLow