What do systematic reviews say?

Summary of findings: levodopa vs other dopamine agonists

Summary of findings: levodopa probably leads to lower number of drop outs due to adverse events compared with other dopamine agonists (moderate certainty).

• Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
  OR 0.59
  3 studies · 504 participants
  Moderate