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What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 4 findings · 1 reviews · Metabolic and Endocrine Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 0 · 0%Moderate 2 · 50%High 0 · 0%

Summary of findings: insulin detemir vs insulin glargine

Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring 00:01‐05:59 (Davies 2014) or 23:00‐07:00 (BEGIN Young)

It is very uncertain whether summary of findings: insulin detemir changes severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with insulin glargine (very low certainty).

1 finding from 1 review

Summary of findings: insulin detemir vs NPH insulin

Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring 00:01‐05:59 (Davies 2014) or 23:00‐07:00 (BEGIN Young)

Summary of findings: insulin detemir showed no clear difference in severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with NPH insulin (moderate certainty).

1 finding from 1 review