Question · asked by 1 review

Summary of findings: insulin detemir vs insulin glargine: Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring 00:01‐05:59 (Davies 2014) or 23:00‐07:00 (BEGIN Young)

It is very uncertain whether summary of findings: insulin detemir changes severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with insulin glargine (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings: insulin detemir vs insulin glargine
Severe nocturnal hypoglycaemia (n/N) Definition: severe hypoglycaemia occurring from 11 p.m. to 6 a.m.
It is very uncertain whether summary of findings: insulin detemir changes severe nocturnal hypoglycaemia (n/N) Definition: severe… compared with insulin glargine (very low certainty).
(Ultra‐)long‐acting insulin analogues for people with type 1 diabetes mellitus (2021) · Cochrane Headline outcomes only
RR 0.55 [0.06, 5.12]2 studies · 763 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
(Ultra‐)long‐acting insulin analogues for people with type 1 diabetes mellitus
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.