Findings

What do systematic reviews say?

48 questions · 48 findings · 2 reviews

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No studies found 24 · 50%GRADE not reported 0 · 0%Very low 12 · 25%Low 5 · 10.4%Moderate 7 · 14.6%High 0 · 0%

Summary of findings: ECM vs ECT

Change in weight (kg) · adults and children with cystic fibrosis

It is very uncertain whether summary of findings: ECM changes change in weight (kg) compared with ECT (very low certainty).

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
MD 0.32
2 studies · 41 participants
Very low

Summary of findings: ECM vs ECT

Change in height · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: all ECMO studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: all ECMO studies compared with conventional care (moderate certainty).

1 finding from 1 review

Extracorporeal membrane oxygenation for critically ill adults 2023 · Cochrane Headline outcomes only
RR 0.8 [0.7, 0.92]
5 studies · 756 participants
Moderate

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VV ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: VV ECMO subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Extracorporeal membrane oxygenation for critically ill adults 2023 · Cochrane Headline outcomes only
RR 0.77 [0.62, 0.96]
2 studies · 429 participants
Moderate

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VA ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: VA ECMO subgroup compared with conventional care (low certainty).

1 finding from 1 review

Extracorporeal membrane oxygenation for critically ill adults 2023 · Cochrane Headline outcomes only
RR 0.5 [0.18, 1.41]
1 study · 42 participants
Low

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality at 6 months (subgroup) · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: ECPR subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Extracorporeal membrane oxygenation for critically ill adults 2023 · Cochrane Headline outcomes only
RR 0.76 [0.52, 1.13]
2 studies · 285 participants
Moderate

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

Major hemorrhage · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to higher major hemorrhage: all available studies compared with conventional care (moderate certainty).

1 finding from 1 review

Extracorporeal membrane oxygenation for critically ill adults 2023 · Cochrane Headline outcomes only
RR 3.32 [1.9, 5.82]
4 studies · 577 participants
Moderate

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

Neurologic injury: all available studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in neurologic injury: all available studies compared with conventional care (moderate certainty).

1 finding from 1 review

Extracorporeal membrane oxygenation for critically ill adults 2023 · Cochrane Headline outcomes only
RR 2.83 [0.36, 22.42]
2 studies · 286 participants
Moderate