Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
Oral steroids showed no clear difference in hearing ‐ return to normal hearing compared with placebo (moderate certainty).
1 finding from 1 review
RR 1.14 [0.97, 1.33]
Studies not reported
Moderate
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
Oral steroids may leads to lower presence/persistence of OME compared with placebo (low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse event: systemic corticosteroid side effects · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether oral steroids changes adverse event: systemic corticosteroid side effects compared with placebo (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
Oral steroids showed no clear difference in presence/persistence of OME (3 to 9 months ‐ medium‐term) № of… compared with no treatment (low certainty).
1 finding from 1 review
RR 1.02 [0.89, 1.17]
Studies not reported
Low
Adverse event: systemic corticosteroid side effects · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of children with clinical adverse event: vertigo · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids showed no clear difference in vertigo compared with placebo (low certainty).
1 finding from 1 review
Dizziness Handicap Inventory score · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
1 finding from 1 review
Caloric extent of recovery (improvement as a % in lateralisation of electronystagmography on caloric testing) · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
2 findings from 1 review
Complete caloric recovery · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids may leads to higher complete caloric recovery compared with placebo (low certainty).
2 findings from 1 review
Adverse effects · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)
1 finding from 1 review
Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss
Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with systemic corticosteroids (low certainty).
1 finding from 1 review
Proportion of patients whose hearing is improved · sudden sensorineural hearing loss
Intratympanic corticosteroids showed no clear difference in proportion of patients whose hearing is improved compared with systemic corticosteroids (moderate certainty).
1 finding from 1 review
Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss
Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with systemic corticosteroids (low certainty).
1 finding from 1 review
Adverse eventsb · sudden sensorineural hearing loss
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Tympanic membrane perforation · sudden sensorineural hearing loss
1 finding from 1 review
Vertigo/dizziness: timing not reported · sudden sensorineural hearing loss
Intratympanic corticosteroids may leads to higher vertigo/dizziness: timing not reportedd compared with systemic corticosteroids (low certainty).
1 finding from 1 review
Vertigo/dizziness: at the time of injection · sudden sensorineural hearing loss
1 finding from 1 review