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Evidence found and GRADE certainty

9 questions · 9 findings · 2 reviews · Eyes and Vision

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No studies found 1 · 11.1%GRADE not reported 0 · 0%Very low 4 · 44.4%Low 2 · 22.2%Moderate 2 · 22.2%High 0 · 0%

Steroids vs lubricants

Change in patient‐reported symptom scores (lower is favored) · people with dry eye

Steroids showed no clear difference in change in patient‐reported symptom scores (lower is favored) compared with lubricants (moderate certainty).

1 finding from 1 review

Steroids vs cyclosporine A

Change in fluorescein corneal staining scores (lower is favored) · people with dry eye

Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with cyclosporine A (low certainty).

1 finding from 1 review

Steroids vs cyclosporine A

Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye

It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with cyclosporine A (very low certainty).

1 finding from 1 review

Steroids vs lubricants

Change in fluorescein corneal staining scores (lower is favored) · people with dry eye

Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with lubricants (moderate certainty).

1 finding from 1 review

Steroids vs lubricants

Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye

It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with lubricants (very low certainty).

1 finding from 1 review

Steroids vs cyclosporine A

Change in patient‐reported symptom scores (lower is favored) · people with dry eye

Steroids showed no clear difference in change in patient‐reported symptom scores (lower is favored) compared with cyclosporine A (low certainty).

1 finding from 1 review

Steroids with or without azathioprine vs cyclosporine A

Proportion of participants experiencing complications or requiring cessation of medication (lower number of events is better) · NIIPPU

It is very uncertain whether steroids with or without azathioprine changes proportion of participants experiencing complications or requiring… compared with cyclosporine A (very low certainty).

1 finding from 1 review