Change in fluorescein corneal staining scores (lower is favored) · people with dry eye
Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with cyclosporine A (low certainty).
1 finding from 1 review
Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye
It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with cyclosporine A (very low certainty).
1 finding from 1 review
Adverse effect: incident elevated IOP ( · people with dry eye
It is very uncertain whether steroids changes adverse effect: incident elevated IOP ( compared with cyclosporine A (very low certainty).
1 finding from 1 review
Adverse effect: cataract · people with dry eye
The review found no eligible studies for this question.
1 finding from 1 review
Change in patient‐reported quality of life scores · people with dry eye
The review found no eligible studies for this question.
1 finding from 1 review
Change in TBUT (seconds) (longer is favored) · people with dry eye
Steroids may leads to higher change in TBUT (seconds) (longer is favored) compared with lubricants (low certainty).
1 finding from 1 review
Change in fluorescein corneal staining scores (lower is favored) · people with dry eye
Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with lubricants (moderate certainty).
1 finding from 1 review
Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye
It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with lubricants (very low certainty).
1 finding from 1 review
Adverse effect: incident elevated IOP ( · people with dry eye
It is very uncertain whether steroids changes adverse effect: incident elevated IOP ( compared with lubricants (very low certainty).
1 finding from 1 review
Adverse effect: cataract · people with dry eye
It is very uncertain whether steroids changes adverse effect: new cataract formation ( compared with lubricants (very low certainty).
1 finding from 1 review
Change in patient‐reported symptom scores (lower is favored) · people with dry eye
Steroids showed no clear difference in change in patient‐reported symptom scores (lower is favored) compared with cyclosporine A (low certainty).
1 finding from 1 review
Change in patient‐reported quality of life scores · people with dry eye
The review found no eligible studies for this question.
1 finding from 1 review
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether topical (intranasal) steroids changes presence/persistence of OME (short‐term); assumed ICC = 0.5 compared with no treatment (very low certainty).
1 finding from 1 review
RR 0.72 [0.57, 0.91]
Studies not reported
Very low
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Resolution of ear discharge ‐ measured at 1 to 2 weeks · chronic suppurative otitis media
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media
1 finding from 1 review