Findings

What do systematic reviews say?

49 questions · 51 findings · 5 reviews

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No studies found 8 · 15.7%GRADE not reported 0 · 0%Very low 11 · 21.6%Low 30 · 58.8%Moderate 2 · 3.9%High 0 · 0%

Steroids vs cyclosporine A

Adverse effect: cataract · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Steroids vs lubricants

Change in patient‐reported quality of life scores · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Steroids vs lubricants

Change in TBUT (seconds) (longer is favored) · people with dry eye

Steroids may leads to higher change in TBUT (seconds) (longer is favored) compared with lubricants (low certainty).

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
MD 0.7 [0.06, 1.34]
7 studies · 587 participants
Low

Steroids vs lubricants

Change in fluorescein corneal staining scores (lower is favored) · people with dry eye

Steroids showed no clear difference in change in fluorescein corneal staining scores (lower is favored) compared with lubricants (moderate certainty).

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
no estimate extracted
15 studies · 3583 participants
Moderate

Steroids vs lubricants

Change in tear osmolarity (mOsm/kg) (lower is favored) · people with dry eye

It is very uncertain whether steroids changes change in tear osmolarity (mOsm/kg) (lower is favored) compared with lubricants (very low certainty).

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
MD 1.6
1 study · 40 participants
Very low

Steroids vs lubricants

Adverse effect: incident elevated IOP ( · people with dry eye

It is very uncertain whether steroids changes adverse effect: incident elevated IOP ( compared with lubricants (very low certainty).

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
RR 5.96 [1.3, 27.38]
8 studies · 2264 participants
Very low

Steroids vs lubricants

Adverse effect: cataract · people with dry eye

It is very uncertain whether steroids changes adverse effect: new cataract formation ( compared with lubricants (very low certainty).

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
RR 0.34 [0.01, 8.22]
3 studies · 1205 participants
Very low

Steroids vs cyclosporine A

Change in patient‐reported symptom scores (lower is favored) · people with dry eye

Steroids showed no clear difference in change in patient‐reported symptom scores (lower is favored) compared with cyclosporine A (low certainty).

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 465 participants
Low

Steroids vs cyclosporine A

Change in patient‐reported quality of life scores · people with dry eye

The review found no eligible studies for this question.

1 finding from 1 review

Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found