Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

607 questions · 641 findings · 77 reviews

No studies found 114 · 17.8%GRADE not reported 25 · 3.9%Very low 170 · 26.5%Low 175 · 27.3%Moderate 123 · 19.2%High 34 · 5.3%

Edaravone plus corticosteroids vs corticosteroids

Reduction in oedema (T2 hyperintensity) · people previously treated with radiosurgery or fractionated radiotherapy to the brain or head and neck region with a diagnosis of brain…

Edaravone plus corticosteroids showed no clear difference in reduction in oedema (T2 hyperintensity) compared with corticosteroids (low certainty).

1 finding from 1 review

Edaravone plus corticosteroids vs corticosteroids

Reduction in post‐gadolinium enhancement · people previously treated with radiosurgery or fractionated radiotherapy to the brain or head and neck region with a diagnosis of brain…

Edaravone plus corticosteroids showed no clear difference in reduction in post‐gadolinium enhancement compared with corticosteroids (low certainty).

1 finding from 1 review

Edaravone plus corticosteroids vs corticosteroids

Improvement in LENT/SOMA · people previously treated with radiosurgery or fractionated radiotherapy to the brain or head and neck region with a diagnosis of brain…

Edaravone plus corticosteroids may leads to higher improvement in LENT/SOMA compared with corticosteroids (low certainty).

1 finding from 1 review

Topical corticosteroids vs placebo or no treatment

Complete resolution of phimosis · boys up to 18 years old with phimosis

Topical corticosteroids may leads to higher complete resolution of phimosis compared with placebo or no treatment (low certainty).

2 findings from 1 review

Inhaled corticosteroids vs no treatment or placebo

Need for nasal continuous positive airway pressure · patients with the management of transient tachypnea of the newborn

It is very uncertain whether inhaled corticosteroids changes need for nasal continuous positive airway pressure compared with no treatment or placebo (very low certainty).

1 finding from 1 review