Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 24 findings · 4 reviews

No studies found 4 · 16.7%GRADE not reported 0 · 0%Very low 7 · 29.2%Low 7 · 29.2%Moderate 6 · 25%High 0 · 0%

Oral steroids vs placebo

Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)

Oral steroids showed no clear difference in hearing ‐ return to normal hearing compared with placebo (moderate certainty).

1 finding from 1 review

Intratympanic corticosteroids vs systemic corticosteroids

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with systemic corticosteroids (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs systemic corticosteroids

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with systemic corticosteroids (low certainty).

1 finding from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes final hearing threshold determined by PTA A lower value represents… compared with systemic corticosteroids alone (very low certainty).

2 findings from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic plus systemic corticosteroids (combined therapy) showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with systemic corticosteroids alone (low certainty).

2 findings from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Proportion of patients whose hearing is improved · sudden sensorineural hearing loss

It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes proportion of patients whose hearing is improved compared with systemic corticosteroids alone (very low certainty).

2 findings from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs no treatment or versus placebo

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with no treatment or versus placebo (low certainty).

1 finding from 1 review

Summary of findings: oral steroids plus antibiotic vs control plus antibiotic

Hearing loss · Children with otitis media with effusion

Summary of findings: oral steroids plus antibiotic showed no clear difference in hearing loss [2 months]1 compared with control plus antibiotic (moderate certainty).

1 finding from 1 review