What do systematic reviews say?

Steroids vs vitamin D

Steroid probably leads to higher number of participants achieving 'clearance' by IGA compared with vitamin D (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.82 [1.52, 2.18]
  4 studies · 2180 participants
  Moderate

Steroids vs vitamin D

Steroid leads to higher number of participants achieving 'response' by IGA compared with vitamin D (high certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 2.09 [1.8, 2.41]
  3 studies · 1827 participants
  High

Steroids vs vitamin D

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Steroids vs vitamin D

Steroid probably leads to lower number of participants withdrawing due to adverse events (AE) compared with vitamin D (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 0.22 [0.11, 0.42]
  4 studies · 2291 participants
  Moderate

Steroids vs vitamin D

Steroid probably leads to higher number of participants achieving 'response' by PGA compared with vitamin D (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.48 [1.28, 1.72]
  3 studies · 1827 participants
  Moderate

Steroid plus vitamin D vs steroids

Steroid plus vitamin D leads to higher number of participants achieving 'response' by PGA compared with steroid (high certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.13 [1.06, 1.2]
  2 studies · 2226 participants
  High

Steroid plus vitamin D vs vitamin D

Steroid plus vitamin D leads to higher number of participants achieving 'clearance' by IGA compared with vitamin D (high certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 2.28 [1.87, 2.78]
  4 studies · 2008 participants
  High

Steroid plus vitamin D vs vitamin D

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with vitamin D (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 2.31 [1.75, 3.04]
  4 studies · 2222 participants
  Moderate

Steroid plus vitamin D vs vitamin D

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Steroid plus vitamin D vs vitamin D

Steroid plus vitamin D leads to lower number of participants withdrawing due to adverse events compared with vitamin D (high certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 0.19 [0.11, 0.36]
  3 studies · 1970 participants
  High

Steroid plus vitamin D vs vitamin D

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by PGA compared with vitamin D (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.76 [1.46, 2.12]
  4 studies · 2222 participants
  Moderate

Steroid plus vitamin D vs steroids

Steroid plus vitamin D probably leads to higher number of participants achieving 'clearance' by IGA compared with steroid (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.22 [1.08, 1.36]
  4 studies · 2474 participants
  Moderate

Steroid plus vitamin D vs steroids

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with steroid (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 1.15 [1.06, 1.25]
  3 studies · 2444 participants
  Moderate

Steroid plus vitamin D vs steroids

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Steroid plus vitamin D vs steroids

Steroid plus vitamin D showed no clear difference in number of participants withdrawing due to adverse events (AE) compared with steroid (moderate certainty).

• Topical treatments for scalp psoriasis 2016 · Cochrane Headline outcomes only
  RR 0.88 [0.42, 1.88]
  3 studies · 2433 participants
  Moderate