Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Airways

No studies found 0 · 0%GRADE not reported 2 · 33.3%Very low 0 · 0%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%

Respiratory exacerbations: number of respiratory exacerbations per year · Adults with COPD

1 finding from 1 review

Statins versus placebo for people with chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 877 participants
Moderate

Exacerbations needing hospitalisation · Adults with COPD

1 finding from 1 review

Statins versus placebo for people with chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 877 participants
Moderate

All‐cause mortality · Adults with COPD

Statins showed no clear difference in all‐cause mortality compared with placebo (low certainty).

1 finding from 1 review

Statins versus placebo for people with chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
OR 1.03 [0.61, 1.74]
2 studies · 952 participants
Low

COPD‐specific mortality · Adults with COPD

Statins showed no clear difference in COPD‐specific mortality compared with placebo (low certainty).

1 finding from 1 review

Statins versus placebo for people with chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
OR 1.25 [0.38, 4.13]
1 study · 877 participants
Low

Quality of life · Adults with COPD

Statins led to lower quality of life compared with placebo; GRADE not reported.

1 finding from 1 review

Statins versus placebo for people with chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
GRADE not reported

Adverse events · Adults with COPD

1 finding from 1 review

Statins versus placebo for people with chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 8 participants
GRADE not reported