Change in neurobehavioral manifestations · children and adults with Smith‐Lemli‐Opitz syndrome
1 finding from 1 review
Statin‐related adverse events · children and adults with Smith‐Lemli‐Opitz syndrome
It is very uncertain whether statins with cholesterol supplementation changes statin‐related adverse events compared with cholesterol supplementation only (very low certainty).
1 finding from 1 review
Growth · children and adults with Smith‐Lemli‐Opitz syndrome
1 finding from 1 review
Changes in biochemical markers plasma dehydrocholesterol levels (mM); plasma cholesterol levels (mM); plasma 7DHC levels (mM); plasma CoQ levels (uM); CSF cholesterol levels (ug/mL); CSF dehydrocholesterol levels (ug/mL) · children and adults with Smith‐Lemli‐Opitz syndrome
1 finding from 1 review
QoL · children and adults with Smith‐Lemli‐Opitz syndrome
The review found no eligible studies for this question.
1 finding from 1 review
All‐cause mortality · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statins showed no clear difference in all‐cause mortality compared with placebo or no treatment (low certainty).
1 finding from 1 review
All cardiovascular death · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statins showed no clear difference in death from cardiovascular causes compared with placebo or no treatment (low certainty).
1 finding from 1 review
Non‐fatal MI · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statins showed no clear difference in myocardial infarction (non‐fatal) compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Stroke/TIA (non‐fatal) · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statins showed no clear difference in stroke/TIA (non‐fatal) compared with placebo or no treatment (low certainty).
1 finding from 1 review
Participant‐reported outcomes－not measured · participants with improving outcomes during and after noncardiac vascular surgery.
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse muscle effects · participants with improving outcomes during and after noncardiac vascular surgery.
1 finding from 1 review