Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 2 reviews · Airways

No studies found 3 · 23.1%GRADE not reported 2 · 15.4%Very low 4 · 30.8%Low 2 · 15.4%Moderate 2 · 15.4%High 0 · 0%

Atorvastatin vs placebo

Asthma exacerbations requiring hospitalisation or a course of steroids · people with asthma

The review found no eligible studies for this question.

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Atorvastatin vs placebo

Health‐related quality of life · people with asthma

The review found no eligible studies for this question.

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Atorvastatin vs placebo

Change in morning PEF (L/min) at endpoint · people with asthma

It is very uncertain whether atorvastatin changes lung function: change in morning PEF compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 12.32
    1 study · 60 participants
    Very low

Atorvastatin vs placebo

Change from baseline in pre‐bronchodilator FEV1 · people with asthma

It is very uncertain whether atorvastatin changes lung function: change in FEV1 (pre) compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 0.13
    1 study · 60 participants
    Very low

Atorvastatin vs placebo

Lung function: change in FEV1 (post) · people with asthma

It is very uncertain whether atorvastatin changes lung function: change in FEV1 (post) compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 0.11
    1 study · 60 participants
    Very low

Atorvastatin vs placebo

Serious adverse events or adverse events · people with asthma

The review found no eligible studies for this question.

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Atorvastatin vs placebo

Asthma control · people with asthma

It is very uncertain whether atorvastatin changes asthma control: change in ACQ compared with placebo (very low certainty).

1 finding from 1 review
  • Statins for asthma 2020 · Cochrane Headline outcomes only
    MD 0.41
    1 study · 60 participants
    Very low