Stroke · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)
Statin probably leads to lower any stroke compared with placebo (moderate certainty).
1 finding from 1 review
Death · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)
Statin probably leads to lower death compared with placebo (moderate certainty).
1 finding from 1 review
Any serious adverse event · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)
Statin showed no clear difference in any serious adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Asthma exacerbations requiring hospitalisation or a course of steroids · people with asthma
The review found no eligible studies for this question.
1 finding from 1 review
Statins for asthma 2020 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · people with asthma
The review found no eligible studies for this question.
1 finding from 1 review
Statins for asthma 2020 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Change in morning PEF (L/min) at endpoint · people with asthma
It is very uncertain whether atorvastatin changes lung function: change in morning PEF compared with placebo (very low certainty).
1 finding from 1 review
Change from baseline in pre‐bronchodilator FEV1 · people with asthma
It is very uncertain whether atorvastatin changes lung function: change in FEV1 (pre) compared with placebo (very low certainty).
1 finding from 1 review
Lung function: change in FEV1 (post) · people with asthma
It is very uncertain whether atorvastatin changes lung function: change in FEV1 (post) compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events or adverse events · people with asthma
The review found no eligible studies for this question.
1 finding from 1 review
Statins for asthma 2020 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Asthma control · people with asthma
It is very uncertain whether atorvastatin changes asthma control: change in ACQ compared with placebo (very low certainty).
1 finding from 1 review
Major cardiovascular event Physicians · Adults with chronic kidney disease not requiring dialysis
Statin therapy leads to lower major cardiovascular events (MACE) compared with placebo or standard of care (high certainty).
1 finding from 1 review
Death · Adults with chronic kidney disease not requiring dialysis
Statin therapy leads to lower death compared with placebo or standard of care (high certainty).
1 finding from 1 review
Rhabdomyolysis · Adults with chronic kidney disease not requiring dialysis
It is very uncertain whether statin therapy changes rhabdomyolysis compared with placebo or standard of care (very low certainty).
1 finding from 1 review
Myocardial infarction · Adults with chronic kidney disease not requiring dialysis
Statin therapy probably leads to lower myocardial infarction compared with placebo or standard of care (moderate certainty).
1 finding from 1 review
Stroke · Adults with chronic kidney disease not requiring dialysis
Statin therapy showed no clear difference in stroke compared with placebo or standard of care (moderate certainty).
1 finding from 1 review
Kidney failure · Adults with chronic kidney disease not requiring dialysis
Statin therapy showed no clear difference in kidney failure compared with placebo or standard of care (moderate certainty).
1 finding from 1 review
Heart failure hospitalisation (RR) · Adults with chronic kidney disease not requiring dialysis
Statin therapy showed no clear difference in hospitalisation due to heart failure compared with placebo or standard of care (low certainty).
1 finding from 1 review
Improvement in acne severity · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
Improvement in testosterone level (nmol/L) after 6 months' treatment · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
Adverse effects · women with polycystic ovary syndrome not actively trying to conceive
1 finding from 1 review
no estimate extracted
2011 participants
GRADE not reported