Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 1 · 25%Moderate 1 · 25%High 0 · 0%

Standard‐dose adrenaline (SDA) vs vasopressin

Return of spontaneous circulation · people suffering cardiac arrest

It is very uncertain whether standard‐dose adrenaline (SDA) changes return of spontaneous circulation compared with vasopressin (very low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 1.1 [0.9, 1.33]
6 studies · 2531 participants
Very low

Standard‐dose adrenaline (SDA) vs SDA plus vasopressin

Return of spontaneous circulation · people suffering cardiac arrest

Standard‐dose adrenaline (SDA) showed no clear difference in return of spontaneous circulation compared with SDA plus vasopressin (low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 0.97 [0.87, 1.08]
3 studies · 3249 participants
Low

Standard‐dose adrenaline (SDA) vs placebo

Return of spontaneous circulation · people suffering cardiac arrest

Standard‐dose adrenaline (SDA) probably leads to higher return of spontaneous circulation compared with placebo (moderate certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 2.86 [2.21, 3.71]
3 studies · 8663 participants
Moderate

Standard‐dose adrenaline (SDA) vs high‐dose adrenaline (HDA)

Return of spontaneous circulation · people suffering cardiac arrest

It is very uncertain whether standard‐dose adrenaline (SDA) changes return of spontaneous circulation compared with high‐dose adrenaline (HDA) (very low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 1.15 [1.02, 1.29]
13 studies · 7014 participants
Very low