What do systematic reviews say?

7 questions · 7 findings · 2 reviews · Dental caries

Sort:Best matchNewest Highest certainty Download CSV

No studies found 4 · 57.1%GRADE not reported 1 · 14.3%Very low 1 · 14.3%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Caries arrest · Children and adults (with or without carious lesions)

Silver diamine fluoride (SDF) plus fluoride varnish showed no clear difference in caries arrest compared with sealants plus fluoride varnish (with or without restorations) (low certainty).

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
24 months · Mixed dentition (coronal)
MD 0.11 [-0.01, 0.22]
1 study · 413 participants
Low

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Secondary prevention of caries · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
No studies reported data for this outcome in this comparison
0 studies
No studies found

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Primary caries prevention · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
No studies reported data for this outcome in this comparison
0 studies
No studies found

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Aesthetics · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
No studies reported data for this outcome in this comparison
0 studies
No studies found

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Adverse effects · Children and adults (with or without carious lesions)

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
Study period (24 months) · Children
Ruff 2022 reported that there were no adverse events during the study period; adverse events were not defined by the study authors. Assumed data available for 1398 participants.
1 study · 1398 participants
Very low

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Dental pain or sensitivity · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes
No studies reported data for this outcome in this comparison
0 studies
No studies found

38% SDF varnish plus oral health instruction vs oral health instruction plus water

new root-surface carious lesions or restorations · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

SDF had a 71% preventative fraction at 36 months; no pooled estimate or GRADE rating was reported.

1 finding from 1 review

A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes
36 months · Hong Kong
Preventative fraction (%) 71
1 study · 306 participants
GRADE not reported