Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Adverse events · chronic pruritus of unknown origin

It is very uncertain whether serlopitant 1 mg changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
RR 1.45 [0.86, 2.47]
1 study · 128 participants
Very low

Adverse events · chronic pruritus of unknown origin

It is very uncertain whether serlopitant 5 mg changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
RR 1.48 [0.87, 2.5]
1 study · 127 participants
Very low

Adverse events · chronic pruritus of unknown origin

It is very uncertain whether serlopitant 0.25 mg changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
RR 1.29 [0.75, 2.24]
1 study · 127 participants
Very low