Self-assembling peptide P11-4 vs CPP-ACP
Remineralization / reduction in lesion severity (change in QLF, laser fluorescence, or lesion area) · Patients with white spot lesions / early caries lesions (WSLs/ECLs), including orthodontic and non-orthodontic lesions, active caries…
Self-assembling peptide P11-4 did not differ significantly from CPP-ACP (SMD -0.38, 95% CI -0.87 to 0.11; indirect evidence only); certainty of evidence not assessed (no GRADE).
1 finding from 1 review
- Comparison of therapies of white spot lesions: a systematic review and network meta-analysis. 2023 All outcomesRCTs (clinical and in vitro); predominantly children and adolescents; orthodontic and non-orthodontic white spot lesions, early caries lesions, and artificial lesionsSMD -0.38 [-0.87, 0.11]Studies not reportedGRADE not reported