Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 3 · 50%Very low 0 · 0%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Second molar at Demirjian stage E at extraction vs Second molar at Demirjian stage F-H at extraction

Spontaneous space closure · Children and adolescents after extraction of a maxillary permanent first molar (before eruption of the second molar)

In the maxilla, extraction at Demirjian stage E (vs later F-H) increases odds of space closure (OR 4.78; low certainty).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Maxilla
OR 4.78 [1.56, 14.66]
3 studies · 252 participants
Low

Second molar at Demirjian stage E at extraction vs Second molar at Demirjian stage F-H at extraction

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, extraction at Demirjian stage E (vs later F-H) increases odds of space closure (OR 3.81; low certainty).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 3.81 [1.85, 7.83]
3 studies · 94 participants
Low

M2 Demirjian stages F-G vs Second molar at Demirjian stage D-E at extraction

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, Demirjian stage F-G vs D-E was not significantly associated with space closure (OR 0.68; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 0.68 [0.28, 1.66]
4 studies
GRADE not reported

Second molar at Demirjian stage A-D at extraction vs Second molar at Demirjian stage G-H at extraction

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, Demirjian stage A-D vs G-H was not significantly associated with space closure (OR 2.75; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 2.75 [0.50, 15.10]
3 studies
GRADE not reported

Second molar at Demirjian stage E-F at extraction vs Second molar at Demirjian stage G-H at extraction

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, Demirjian stage E-F vs G-H was not significantly associated with space closure (OR 4.44; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 4.44 [0.43, 46.10]
3 studies
GRADE not reported

Second molar at Demirjian stage A-D at extraction vs Second molar at Demirjian stage F-H at extraction

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, earlier Demirjian stage A-D (vs F-H) increases odds of space closure (OR 3.11; low certainty).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 3.11 [1.25, 7.72]
3 studies · 95 participants
Low