Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

99 questions · 101 findings · 5 reviews

No studies found 37 · 36.6%GRADE not reported 6 · 5.9%Very low 16 · 15.8%Low 18 · 17.8%Moderate 24 · 23.8%High 0 · 0%

Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)

Adverse events ‐ hyperpigmentation ( · people with telangiectasias and reticular veins

Sclerotherapy (hypertonic glucose plus polidocanol) showed no clear difference in adverse events ‐ hyperpigmentation ( compared with sclerotherapy (hypertonic glucose) (moderate certainty).

1 finding from 1 review

Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)

Adverse events ‐ matting ( · people with telangiectasias and reticular veins

Sclerotherapy (hypertonic glucose plus polidocanol) showed no clear difference in adverse events ‐ matting ( compared with sclerotherapy (hypertonic glucose) (moderate certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs SFJ ligation and stripping (HL/S)

Technical success · people with GSV incompetence

Ultrasound‐guided foam sclerotherapy (UGFS) may leads to lower technical success (< 5 years) compared with SFJ ligation and stripping (HL/S) (low certainty).

2 findings from 1 review