Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 1 · 25%Very low 1 · 25%Low 0 · 0%Moderate 1 · 25%High 1 · 25%

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

It is very uncertain whether SSRIs changes failure to respond compared with benzodiazepines (very low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 0.93 [0.48, 1.8]
1 study · 154 participants
Very low

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

SSRIs showed no clear difference in failure to respond compared with MAOIs (moderate certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.12 [0.83, 1.52]
2 studies · 396 participants
Moderate

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

SSRIs showed no clear difference in failure to respond compared with SNRIs (high certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 0.96 [0.75, 1.23]
2 studies · 991 participants
High

Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported