Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

15 questions · 18 findings · 2 reviews

No studies found 3 · 16.7%GRADE not reported 10 · 55.6%Very low 4 · 22.2%Low 0 · 0%Moderate 1 · 5.6%High 0 · 0%

Resin-based fissure sealant vs Fluoride varnish

Time taken to apply pit and fissure sealant or fluoride varnish · Children and adolescents (general population, aged under 20 years)

The review found no eligible studies for this question.

1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Time taken to apply pit and fissure sealant or fluoride varnish · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Safety of sealants and fluoride varnishes (adverse events) · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Number of visits to the dentist for repair of sealant or fluoride varnish application · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant led to higher number of visits to the dentist for repair of sealant or fluoride… compared with fluoride varnish; GRADE not reported.

1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Number of visits to the dentist for repair of sealant or fluoride varnish application · Children and adolescents (general population, aged under 20 years)

The review found no eligible studies for this question.

1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Change in DMFT (decayed, missing and filled permanent teeth) increment · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant led to lower change in DMFT (decayed, missing and filled permanent teeth) increment compared with fluoride varnish; GRADE not reported.

1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Change in DMFS (decayed, missing and filled permanent surfaces) increment · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant led to lower change in DMFS (decayed, missing and filled permanent surfaces)… compared with fluoride varnish; GRADE not reported.

1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant changes dentine caries in permanent molars (yes/no) compared with fluoride varnish (very low certainty).

1 finding from 1 review

Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment)

Caries on occlusal surfaces of permanent molars (12 months) · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant (2nd/3rd/4th generation) led to lower caries on occlusal surfaces of permanent molars (36 months) compared with no sealant (control/no treatment); GRADE not reported.

3 findings from 1 review

Resin-based fissure sealant (2nd/3rd/4th generation) vs No sealant (control/no treatment)

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant (2nd/3rd/4th generation) probably leads to lower dentine caries in permanent molars (24 months) compared with no sealant (control/no treatment) (moderate certainty).

1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Progression of dentinal carious lesions into enamel or dentine · Children and adolescents (general population, aged under 20 years)

The review found no eligible studies for this question.

1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Changes in decayed, missing and filled (DMF) figures at whole-mouth level · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant plus fluoride varnish changes dentine caries in permanent molars (yes/no) compared with fluoride varnish alone (very low certainty).

1 finding from 1 review

Resin-based fissure sealant (visible-light-polymerized) vs Fluoride varnish

Incidence of dentinal carious lesion on treated occlusal surfaces of molars or premolars (yes/no) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant (visible-light-polymerized) changes incidence of dentinal carious lesion on treated occlusal surfaces of… compared with fluoride varnish (very low certainty).

2 findings from 1 review