What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Dental caries

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Resin infiltration vs Pre-treatment baseline before infiltration (T0); pooled as a within-arm before/after change

Lightness/brightness change of white spot lesion (luminosity L*, T0 to T1) · Patients with post-orthodontic white spot lesions and permanent dentition

ICON resin infiltration showed no statistically significant change in lightness/brightness of post-orthodontic white spot lesions at 6 months (pooled Cohen's d/SMD -0.001, 95% CI -0.23 to 0.23; 3 studies, 330 teeth; I2=97%); not GRADE-rated.

1 finding from 1 review

Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… 2022 All outcomes
6 months · Post-orthodontic patients after fixed appliance removal; permanent dentition; in vivo clinical trials
SMD -0.001 [-0.23, 0.23]
3 studies · 330 participants
GRADE not reported

Resin infiltration vs Pre-treatment baseline before infiltration (T0); pooled as a within-arm before/after change

Color change of white spot lesion (color difference, T0 to T1) · Patients with post-orthodontic white spot lesions and permanent dentition

ICON resin infiltration significantly improved the color of post-orthodontic white spot lesions at 6 months (pooled Cohen's d/SMD 1.36, 95% CI 1.14 to 1.59; 4 studies, 458 teeth), although heterogeneity was very high (I2=98%) with a heavy outlier (Kannan); not GRADE-rated.

1 finding from 1 review

Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… 2022 All outcomes
6 months · Post-orthodontic patients after fixed appliance removal; permanent dentition; in vivo clinical trials
SMD 1.36 [1.14, 1.59]
4 studies · 458 participants
GRADE not reported