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What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 7 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 71.4%Low 2 · 28.6%Moderate 0 · 0%High 0 · 0%

Rapid vs slow withdrawal of antiepileptic drugs

Seizure freedom · people with epilepsy

It is very uncertain whether rapid changes seizure freedom after 1 year of AED withdrawal compared with slow withdrawal of antiepileptic drugs (very low certainty).

3 findings from 1 review

Rapid vs slow taper of buprenorphine dose

Completion of withdrawal treatment − Outpatient · Adults or adolescents with opioid dependence

It is very uncertain whether rapid changes completion of withdrawal treatment − Outpatient compared with slow taper of buprenorphine dose (very low certainty).

1 finding from 1 review

Rapid vs slow taper of buprenorphine dose

Number abstinent at completion of dose taper − Outpatient · Adults or adolescents with opioid dependence

It is very uncertain whether rapid changes number abstinent at completion of dose taper − Outpatient compared with slow taper of buprenorphine dose (very low certainty).

1 finding from 1 review

Rapid vs slow taper of buprenorphine dose

Completion of withdrawal treatment − Inpatient · Adults or adolescents with opioid dependence

Rapid showed no clear difference in completion of withdrawal treatment − Inpatient compared with slow taper of buprenorphine dose (low certainty).

1 finding from 1 review