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Evidence found and GRADE certainty

6 questions · 13 findings · 2 reviews

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No studies found 1 · 7.7%GRADE not reported 12 · 92.3%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Quantitative light-induced fluorescence (QLF) vs Reference standard

detection of occlusal caries · human primary or permanent teeth with dental caries lesions

QLF had pooled sensitivity of 0.86 and specificity of 0.80 for occlusal caries (permanent dentition, in vivo).

2 findings from 1 review

Quantitative light-induced fluorescence (QLF) vs Reference standard (bitewing radiography, ADA classification, ICDAS II)

Occlusal caries detection: specificity · Patients (in vivo); permanent and primary teeth, occlusal surfaces

In vivo, QLF pooled specificity for occlusal caries in permanent teeth was 0.80 (3 studies; ungraded).

2 findings from 1 review

Quantitative light-induced fluorescence (QLF) vs Reference standard (histology; some ICDAS/radiography)

Occlusal caries detection: sensitivity · Extracted human teeth (in vitro); permanent and primary teeth, occlusal surfaces

In vitro, QLF pooled sensitivity for occlusal caries detection was 0.83 (5 studies; ungraded).

3 findings from 1 review

Quantitative light-induced fluorescence (QLF) vs Reference standard (histology; some ICDAS/radiography)

Occlusal caries detection: specificity · Extracted human teeth (in vitro); permanent and primary teeth, occlusal surfaces

In vitro, QLF pooled specificity for occlusal caries in permanent teeth was 0.66 (3 studies; ungraded).

3 findings from 1 review

Quantitative light-induced fluorescence (QLF) vs Reference standard (bitewing radiography, ADA classification, ICDAS II)

Occlusal caries detection: sensitivity · Patients (in vivo); permanent and primary teeth, occlusal surfaces

In vivo, QLF pooled sensitivity for occlusal caries detection was 0.86 (4 studies; ungraded).

2 findings from 1 review

Quantitative light-induced fluorescence (QLF) vs Histological validation (in vitro) or cavity preparation/biopsy (in vivo)

Occlusal caries detection accuracy · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

No eligible QLF studies met the meta-analysis inclusion criteria (candidate QLF studies were identified but none had acceptable index/reference tests and reporting quality).

1 finding from 1 review