Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy showed no clear difference in clinical failure compared with 3Mix pulpectomy; GRADE not reported.
1 finding from 1 review
Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy showed no clear difference in radiological failure compared with 3Mix pulpectomy; GRADE not reported.
1 finding from 1 review
Tooth survival · Children with carious vital pulp exposure in primary incisors
Tooth survival was reported narratively in two trials and was not pooled.
1 finding from 1 review
Pathological periapical radiolucency · Children with carious vital pulp exposure in primary incisors
Two trials reported periapical radiolucency but results were not pooled owing to considerable heterogeneity.
1 finding from 1 review
Clinical failure · Children with carious vital pulp exposure in primary incisors
Pulpotomy may not differ from pulpectomy for clinical failure; no GRADE rating was reported.
1 finding from 1 review
Soft tissue pathology · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in soft tissue pathology between pulpotomy and pulpectomy (RR 3.11, 95% CI 0.54 to 17.7; ungraded).
1 finding from 1 review
RR 3.11 [0.54, 17.7]
Studies not reported
GRADE not reported
Pathological mobility · Children with carious vital pulp exposure in primary incisors
Pathological mobility was rare (one tooth in one of four trials) and was not pooled.
1 finding from 1 review
Pathological root resorption · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in pathological root resorption between pulpotomy and pulpectomy (RR 1.5, 95% CI 0.56 to 4.04; ungraded).
1 finding from 1 review
RR 1.5 [0.56, 4.04]
2 studies
GRADE not reported
Radiographic failure · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in radiographic failure between pulpotomy and pulpectomy in the main analysis (RR 0.79, 95% CI 0.25 to 2.42), with considerable heterogeneity (I2=76%; ungraded).
2 findings from 1 review
Pain · Children with carious vital pulp exposure in primary incisors
No statistically significant difference in pain between pulpotomy and pulpectomy (RR 2.06, 95% CI 0.31 to 13.8; ungraded).
1 finding from 1 review
RR 2.06 [0.31, 13.8]
Studies not reported
GRADE not reported
Pulp canal obliteration · Children with carious vital pulp exposure in primary incisors
Pulp canal obliteration was reported narratively (mainly in the pulpotomy group) and was not pooled.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
The three-study meta-analysis found no significant difference between full and partial pulpotomy after 1 year.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure
Full pulpotomy showed a non-significant trend toward higher success than partial pulpotomy in mature teeth with irreversible pulpitis (ungraded).
1 finding from 1 review
OR 2.16 [0.92, 5.07]
3 studies
GRADE not reported
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Biodentine had a significantly higher pulpotomy success rate than CEM (indirect comparison; numeric estimate not available); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Biodentine had a significantly higher pulpotomy success rate than calcium hydroxide (indirect comparison; numeric estimate not available); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Biodentine had a significantly higher pulpotomy success rate than MTA (indirect comparison; numeric estimate not available); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
Hemostasis within 6 min gave the highest success (90.4%), but the difference across hemostasis-time groups was not significant (ungraded).
13 findings from 1 review
Show 10 more findings
Proportion 0.856
Studies not reported
GRADE not reported
Proportion 0.862
Studies not reported
GRADE not reported
Proportion 0.824 [0.746, 0.890]
Studies not reported
GRADE not reported
Proportion 0.909 [0.833, 0.965]
Studies not reported
GRADE not reported
Proportion 0.882
Studies not reported
GRADE not reported
Proportion 0.867 [0.820, 0.907]
25 studies · 2012 participants
Very low
Proportion 0.902
Studies not reported
GRADE not reported
Proportion 0.838 [0.759, 0.904]
Studies not reported
GRADE not reported
Proportion 0.872 [0.803, 0.929]
Studies not reported
GRADE not reported
Proportion 0.859
Studies not reported
GRADE not reported
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis due to carious pulp exposure
Among 6 observational studies, pooled pulpotomy success was 92.6 per 100 (95% CI 0.86-0.96), very low certainty.
4 findings from 1 review
Show 1 more finding
Overall success (composite of clinical and radiographic success) · Human permanent teeth with asymptomatic irreversible pulpitis due to carious pulp exposure
In asymptomatic irreversible pulpitis, pooled pulpotomy success was 91.3% (95% CI 80-96.5%); ungraded.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Human permanent teeth with irreversible pulpitis and open (immature) root apex due to carious pulp exposure
In open-apex teeth, pooled pulpotomy success was 95.8% (95% CI 81-99%); significantly higher than closed apex (z=2.33, p=0.02); ungraded.
1 finding from 1 review