What do systematic reviews say?

Psychotherapy as an adjunct to usual care vs usual care

• Psychological therapies for treatment‐resistant depression in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 248 participants
  Low
• Psychological therapies for treatment‐resistant depression in adults 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 252 participants
  Low

Psychotherapy as an adjunct to usual care vs usual care

Psychotherapy as an adjunct to usual care may leads to lower dropout long term (longer than 12 months)* compared with usual care alone (low certainty).

• Psychological therapies for treatment‐resistant depression in adults 2018 · Cochrane Headline outcomes only
  RR 0.8 [0.66, 0.97]
  1 study · 469 participants
  Low

Psychotherapy as an adjunct to usual care vs usual care

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) long term (longer than 12 months)* compared with usual care alone (low certainty).

• Psychological therapies for treatment‐resistant depression in adults 2018 · Cochrane Headline outcomes only
  RR 1.62 [1.13, 2.32]
  1 study · 248 participants
  Low

Psychotherapy as an adjunct to usual care vs usual care

Psychotherapy as an adjunct to usual care showed no clear difference in remission (< 7 on HAMD or < 10 on BDI) long term (longer than 12… compared with usual care alone (low certainty).

• Psychological therapies for treatment‐resistant depression in adults 2018 · Cochrane Headline outcomes only
  RR 1.56 [0.97, 2.53]
  1 study · 248 participants
  Low