Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

41 questions · 41 findings · 1 reviews

No studies found 12 · 29.3%GRADE not reported 0 · 0%Very low 13 · 31.7%Low 16 · 39%Moderate 0 · 0%High 0 · 0%

Progesterone vs no treatment or placebo (route of progesterone administration)

Live birth or ongoing pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in live birth/ongoing pregnancy rate compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Miscarriage per clinical pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in miscarriage per clinical pregnancy compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Clinical pregnancy · women trying to conceive by intrauterine insemination

Progesterone may leads to higher clinical pregnancy per woman compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Clinical pregnancy per woman ‐ oral route · women trying to conceive by intrauterine insemination

It is very uncertain whether progesterone changes clinical pregnancy per woman ‐ oral route compared with no treatment or placebo (route of progesterone administration) (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in multiple pregnancy per woman compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Intramuscular (IM) progesterone vs vaginal progesterone

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether intramuscular (IM) progesterone changes clinical pregnancy rate compared with vaginal progesterone (very low certainty).

1 finding from 1 review