Findings

What do systematic reviews say?

4 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 50%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Clinical cure · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs may leads to higher clinical cure rate (short‐term) compared with conventional antifungal drugs (low certainty).

2 findings from 1 review

Probiotics for vulvovaginal candidiasis in non‐pregnant women 2017 · Cochrane Headline outcomes only
RR 1.14 [1.05, 1.24]
5 studies · 695 participants
Low
Probiotics for vulvovaginal candidiasis in non‐pregnant women 2017 · Cochrane Headline outcomes only
RR 1.07 [0.86, 1.33]
1 study · 172 participants
Very low

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Mycological cure · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs may leads to higher mycological cure rate (short‐term) compared with conventional antifungal drugs (low certainty).

2 findings from 1 review

Probiotics for vulvovaginal candidiasis in non‐pregnant women 2017 · Cochrane Headline outcomes only
RR 1.06 [1.02, 1.1]
7 studies · 969 participants
Low
Probiotics for vulvovaginal candidiasis in non‐pregnant women 2017 · Cochrane Headline outcomes only
RR 1.26 [0.93, 1.71]
3 studies · 627 participants
Very low

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Relapse · non‐pregnant women with vulvovaginal candidiasis

It is very uncertain whether probiotics used as adjuvants to conventional antifungal drugs changes relapse rate compared with conventional antifungal drugs (very low certainty).

1 finding from 1 review

Probiotics for vulvovaginal candidiasis in non‐pregnant women 2017 · Cochrane Headline outcomes only
RR 0.34 [0.17, 0.68]
3 studies · 388 participants
Very low

Probiotics used as adjuvants to conventional antifungal drugs vs conventional antifungal drugs

Rate of serious adverse events · non‐pregnant women with vulvovaginal candidiasis

Probiotics used as adjuvants to conventional antifungal drugs showed no clear difference in rate of serious adverse events compared with conventional antifungal drugs (low certainty).

1 finding from 1 review

Probiotics for vulvovaginal candidiasis in non‐pregnant women 2017 · Cochrane Headline outcomes only
RR 0.8 [0.22, 2.94]
2 studies · 440 participants
Low