Gestational age (preterm birth < 37 weeks) · preterm infants
Probiotics administered to pregnant women at risk of preterm birth showed no clear difference in preterm birth < 37 weeks' gestation compared with placebo or no intervention (low certainty).
1 finding from 1 review
Culture‐proven sepsis with supplemented probiotic · preterm infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Preterm birth less than 34 weeks' gestation · preterm infants
1 finding from 1 review
Gestational age at birth (weeks) · preterm infants
1 finding from 1 review
Death · preterm infants
1 finding from 1 review
Miscarriage/stillbirth · preterm infants
Probiotics administered to pregnant women at risk of preterm birth showed no clear difference in miscarriage/stillbirth compared with placebo or no intervention (low certainty).
1 finding from 1 review
Neonatal sepsis ≤ 3 days · preterm infants
1 finding from 1 review
NEC ≥ stage II · preterm infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death or severe NEC · preterm infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Any late‐onset sepsis ‐ all infants · preterm infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · prevention of sepsis and necrotizing enterocolitis in preterm infants
It is very uncertain whether lactoferrin supplementation with enteral feeds in combination with… changes all‐cause mortality compared with placebo (very low certainty).
1 finding from 1 review
Bacterial sepsis · prevention of sepsis and necrotizing enterocolitis in preterm infants
Lactoferrin supplementation with enteral feeds in combination with… may leads to lower bacterial sepsis compared with placebo (low certainty).
1 finding from 1 review
Fungal Infection · prevention of sepsis and necrotizing enterocolitis in preterm infants
Lactoferrin supplementation with enteral feeds in combination with… may leads to lower fungal Infection compared with placebo (low certainty).
1 finding from 1 review
Chronic lung disease · prevention of sepsis and necrotizing enterocolitis in preterm infants
It is very uncertain whether lactoferrin supplementation with enteral feeds in combination with… changes chronic lung disease compared with placebo (very low certainty).
1 finding from 1 review
Length of stay among survivors · prevention of sepsis and necrotizing enterocolitis in preterm infants
1 finding from 1 review
Any late‐onset sepsis ‐ All infants [Data on only confirmed sepsis available] · prevention of sepsis and necrotizing enterocolitis in preterm infants
Lactoferrin supplementation with enteral feeds in combination with… may leads to lower any late‐onset sepsis ‐ All infants [Data on only confirmed sepsis… compared with placebo (low certainty).
1 finding from 1 review
NEC ≥ stage II · prevention of sepsis and necrotizing enterocolitis in preterm infants
It is very uncertain whether lactoferrin supplementation with enteral feeds in combination with… changes NEC ≥ stage II compared with placebo (very low certainty).
1 finding from 1 review
Necrotising enterocolitis · preterm infants
Probiotics administered exclusively after birth in mothers of… showed no clear difference in any necrotizing Enterocolitis (NEC) compared with maternal placebo or no intervention (low certainty).
1 finding from 1 review
Mortality before hospital discharge · preterm infants
Probiotics administered exclusively after birth in mothers of… showed no clear difference in death prior to hospital discharge compared with maternal placebo or no intervention (low certainty).
1 finding from 1 review
Death or NEC · preterm infants
Probiotics administered exclusively after birth in mothers of… showed no clear difference in death or NEC compared with maternal placebo or no intervention (low certainty).
1 finding from 1 review