Probiotics vs placebo
Clinical remission · people with active UC
Probiotics may leads to higher clinical remission compared with placebo (low certainty).
1 finding from 1 review
- RR 1.73 [1.19, 2.54]9 studies · 594 participantsLow
Findings
What do systematic reviews say?
5 questions · 5 findings · 3 reviews
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 40%Low 3 · 60%Moderate 0 · 0%High 0 · 0%
Probiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)
Clinical remission · people with active UC
Probiotics showed no clear difference in clinical remission compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (low certainty).
1 finding from 1 review
- RR 0.92 [0.73, 1.16]1 study · 116 participantsLow
Probiotics vs placebo
Maintenance of clinical remission · Patients with quiescent ulcerative colitis
It is very uncertain whether probiotics changes maintenance of clinical remission (52 weeks) compared with placebo (very low certainty).
1 finding from 1 review
- Probiotics for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes onlyRR 1.16 [0.98, 1.37]2 studies · 141 participantsVery low
Probiotics vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)
Maintenance of clinical remission · Patients with quiescent ulcerative colitis
Probiotics showed no clear difference in maintenance of clinical remission (52 weeks) compared with 5‐aminosalicylic acid (5‐ASA) (mesalazine) (low certainty).
1 finding from 1 review
- Probiotics for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes onlyRR 1.06 [0.9, 1.25]1 study · 125 participantsLow
Antibiotics plus probiotics vs placebo or no intervention
Failure to induce clinical remission at end of study · people with active UC
It is very uncertain whether antibiotics plus probiotics changes failure to induce clinical remission at end of study compared with placebo or no intervention (very low certainty).
1 finding from 1 review
- Antibiotics for the induction and maintenance of remission in ulcerative colitis 2022 · Cochrane Headline outcomes onlyRR 0.68 [0.39, 1.19]2 studies · 98 participantsVery low