Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · All outcomes

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No studies found 0 · 0%GRADE not reported 1 · 50%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Preoperative paracetamol (acetaminophen) vs placebo

Postoperative pain (dichotomous measure: parent report of presence of pain-related behaviours) · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)

Preoperative paracetamol (acetaminophen) showed no clear difference in postoperative pain (dichotomous measure: parent report of presence… compared with placebo (low certainty).

1 finding from 1 review

Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
Mean 6.5 hours
RR 0.81 [0.53, 1.22]
2 studies · 100 participants
Low

Preoperative paracetamol (acetaminophen) vs placebo

Adverse events · Children and adolescents having dental treatment under local anaesthetic (restorative and extraction treatments)

1 finding from 1 review

Preoperative analgesics for additional pain relief in children and adolescents having dental treatment 2016 · Cochrane All outcomes
No adverse events were recorded in Primosch 1995. The other two studies did not mention adverse events.
1 study
GRADE not reported