Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 1 · 25%High 1 · 25%

Praziquantel 40 mg/kg vs placebo

Parasitological failure At 1 to 2 months · people with urinary schistosomiasis

Praziquantel 40 mg/kg leads to lower parasitological failure At 1 to 2 months compared with placebo (high certainty).

1 finding from 1 review

Drugs for treating urinary schistosomiasis 2014 · Cochrane Headline outcomes only
RR 0.42 [0.29, 0.59]
7 studies · 864 participants
High

Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose

Parasitological failure at 1 month · people with urinary schistosomiasis

Praziquantel 40 mg/kg single dose may leads to lower parasitological failure At 1 month compared with 30 mg/kg single dose (low certainty).

1 finding from 1 review

Drugs for treating urinary schistosomiasis 2014 · Cochrane Headline outcomes only
RR 0.76 [0.59, 0.99]
4 studies · 401 participants
Low

Praziquantel 40 mg/kg single dose vs 30 mg/kg single dose

Parasitological failure At 6 months · people with urinary schistosomiasis

Praziquantel 40 mg/kg single dose showed no clear difference in parasitological failure At 6 months compared with 30 mg/kg single dose (moderate certainty).

1 finding from 1 review

Drugs for treating urinary schistosomiasis 2014 · Cochrane Headline outcomes only
RR 0.97 [0.76, 1.23]
6 studies · 669 participants
Moderate

Artesunate (12 mg/kg) plus praziquantel (40 mg/kg) vs praziquantel

Parasitological failure at 1 month · People with S. mansoni infection

It is very uncertain whether artesunate (12 mg/kg) plus praziquantel (40 mg/kg) changes parasitological failure at 1 month compared with praziquantel (40 mg/kg) alone (very low certainty).

1 finding from 1 review

Drugs for treating Schistosoma mansoni infection 2013 · Cochrane Headline outcomes only
RR 0.62 [0.35, 1.09]
1 study · 75 participants
Very low